In early you want to stack up your grasp with your E as much as you can since it gives range to the next autos and will most likely outrange most of the toplaners, always try to keep your Q stacks and don't use them to farm, if the enemy try to trade back when you go for the E poke you'll always have an advantage, and by that time your E will be back up to disengage

In mid game you really just want to split and have your tp up for objectives, since in this stage of the game you won't be tanky enough already.

In late game is where this build really shines, with the % max health dmg and true dmg your kit provides you will be able to shred tanks whil being tanky enough yourself, you can also go on squishys or just try to bait out as many important abilities as you can from the enemy team, the most important part is just using your W when a CC that will get you killed comes, if it's just dmg don't worry you can tank it.