This is what is known as a pure hard counter; very good ban for any Karthus firstpick. The only window to somewhat do anything is pre 6, since after she unlocks her own 6 she begins to oneshot you in your own jungle.
Most evelynn players look to use first ult on botlane, but since you are Karthus she will instead probably look to use first ult on you to get stacks and disrupt your sequence.
Kindred
At start of champ select pray to the gods enemy Kindred is bad because if they are OTP or semi decent u cannot play the game. Ultimate is insane hardcounter and means even if she gets behind 0 marks she still is useful. It also enables her to perma invade you after 6 for free 300 gold sacks and still live because of ult. Red buff slow ubercucks you and can destroy you with Q mobility early on, do not attempt to duel this champion as she will dodge every single Q and run you over.
Kha'Zix
Kha'Zix will perma invade you on camp spawns and one shot you every time, also a very good ban. Not much you can do if he invades. Can take exh/red smite to try and duel.
Graves
W is hard counter as it blocks vision in your passive, very scary to deal with early and if he invades u probably die to redbuff aa.
Before season 13 Graves was absolutely unplayable, but in recent patches the matchup has become much more bearable (I've even stopped banning this champion). There is room for outplay with Q placement now, and with nerfs to mr items and Graves players going bruiser instead of lethality now, matchup has become somewhat playable.
Nidalee
Nidalee destroys you, if she gets ahead she can easily perma invade and pressure you and have 3x your tempo. Can take null orb in runes and go redsmite if u have mental block/problems with her. You hard outscale.
Nocturne
Terrible matchup, he can block your R with spellshield, after 6 every time u show u die, honestly just dodge, otherwise perma avoid/ group with team and try to outscale.
Lee Sin
Dodge Q and kite, he can duel and kill you easily but so can you. You hard outscale, just dont die early levels.
Rengar
Kha’Zix but a bit easier to play vs, he can easily pick you before team fights in your own jungle with R, recommend buy zhonyas 2nd as it hardcounters him.
Zac
Disgusting champion, try to perma invade and countergank, if you invade him he can do nothing, he gets low on clears so just go kill him. He outscales you late as he becomes near unkillable doing 60% max HP magic damage to 5 people.
Xin Zhao
A miserable experience, just try and avoid and out scale, if you meet him early try to W/smite and kite him, objective is to survive
Rek'Sai
If she gets onto you u die insta, pretty horrible experience to play vs but her window to win vs you is gone after min 20 where she becomes cannon minion so just try avoid and out scale like Xin
Shaco
Champ that will just go ur jungle and kill you perma, the one matchup u can go exhaust vs since u likely win duel if u use it. Try to stay healthy in clears as he takes ignite to ruin ur smite heal in fights.
Kayn
You can easily outjungle and outfarm Kayn, if you’re confident go invade Kayn can’t fight u before form. If Rhaast just build to kill and kite, if SA Zhonyas and treat like khazix; SA is quite weak atm though but is getting buffed next patch and this placement may change.
Ivern
U get free farm and free scaling, problem is his scaling and his enchanter nature hardcounters you
Hecarim
Can match your clear speed but you win duel if you're good, he is easily kited and dies easily before he picks up some magic resist. Don’t allow him to get ahead though because then he will just run you over.
Ekko
For five season this was the go to high elo pick into Karthus with near Evelynn levels of no counter play. However, the Q buffs of 12.11 changed much and so he can no longer keep up with your clearspeed/tempo. If played correctly u can avoid him, just beware he can perma invade and live because of R, also scales insanely well too so do not allow him to get fed or stack his Dseal.
Fiddlesticks
Inferior Karthus in almost every way except his utility he brings to team fight, you out duel, out gank, out clear and can go perma invade.
Warwick
You should be 40-50 cs ahead at all times, his clear is so bad after s11 Tiamat rework that he literally cannot keep up with u no matter what.
Amumu
Same as fiddle, except he can actually duel you if he hits Q. Otherwise useless.
Diana
Nunu & Willump
Spam ping your team the moment you think he’s gonna gank, nunu has 1 gameplan and that is to coin flip as much ganks before min 20 as possible at that point he turns into a tank and you are 100 cs ahead 10cspm.
Olaf
Piss easy matchup, you out farm out scale and if u have hands u easily kite and one shot. Only window he has is to invade ur red 2:40 so just do the 1:14 ward and take free LP.
Volibear
Same as Olaf
Trundle
Same as Olaf
Gragas
Olaf but even easier
Master Yi
Care 2:40 invade so do the 1:14 ward, otherwise go out farm and out scale, go Zhonyas and when he Qs on you just press QW and watch his HP bar disappear
Skarner
Same as Olaf except can pick you with his ult (usually its a good thing if he drags u into his team) just dont get picked before fights.
Elise
Honestly garbage champ in this meta, just care the usual invades dont get one shot by her and go flame horizon cs gap and outscale past min 15
Udyr
out farm and outscale, dont get cheese invaded, if he gets onto you you are usually just dead
Jarvan IV
Outscale outfarm should be easy pz just ping ur laners like nunu care his level 2/3 force ganks, if he doesn’t go for 3 camp into gank care the 2:40 invade.
Shyvana
You do the same things she does but slightly better if she goes AP. In current meta shyvana struggles to keep up tempo with karthus so you should be able to force plays early. At 6 she gains huge powerspike and the option to counterjungle/take initiative. If she goes AD she can oneshot you with PTA so care for early invades. AP is the same except u don't need to respect invades as early (only after 1-2 components/mythic).
Lillia
Thank god this champ is nerfed what an abomination to play vs. U can kite her with bluesmite + q as it steals her bonus MS from Q stacks, don't get picked early, you outscale.
Talon
Commonly known boosting strategy, you two synergise so well, Talon dominates lane and can defend Karthus from enemy invades, your AP/AD heavy damage natures complement each other really well, R helps secure his assassinations, should be free early for you, the duo also scales insanely into late.
Leona
CC for your unloading of damage
Zed
Budget Talon
Qiyana
Budget Talon except can help set up your damage with ice element. Insane teamfight potential but u may need to help her a bit instead of just afk farm and wait for her to come def you.
Nocturne
Talon but cant dominate lane as hard after nerfs, but can become your personal bodyguard after level 6 as he ults towards enemy gluesniffer jgler trying to invade u.
Vladimir
If rest of the team is sufficient early and AD heavy you can draft Vlad Karthus and 2v5 lategame fights
Soraka
Sounds very troll but you get 2 global Rs allowing u to dominate sidelanes (draft like nocturne mid), can go 1 3 1 to win ez, also prevents enemy from picking soraka.
Nautilus
See Leona
Synergies
IdealStrongOkLowNone
Talon
Commonly known boosting strategy, you two synergise so well, Talon dominates lane and can defend Karthus from enemy invades, your AP/AD heavy damage natures complement each other really well, R helps secure his assassinations, should be free early for you, the duo also scales insanely into late.
Leona
CC for your unloading of damage
Zed
Budget Talon
Qiyana
Budget Talon except can help set up your damage with ice element. Insane teamfight potential but u may need to help her a bit instead of just afk farm and wait for her to come def you.
Nocturne
Talon but cant dominate lane as hard after nerfs, but can become your personal bodyguard after level 6 as he ults towards enemy gluesniffer jgler trying to invade u.
Vladimir
If rest of the team is sufficient early and AD heavy you can draft Vlad Karthus and 2v5 lategame fights
Soraka
Sounds very troll but you get 2 global Rs allowing u to dominate sidelanes (draft like nocturne mid), can go 1 3 1 to win ez, also prevents enemy from picking soraka.
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