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LoL Best Vayne Build Guides 2024

Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!



Season 14 Guides // Patch 14.21
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

An Orbwalker's Guide to Vayne

Guide by frreddi updated October 29, 2024
Season 14 Guides // Other Patches
8.6
584
Votes
54
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

<Master> S13 LostFish - Vayne: On Wings of Night (working on update)

Guide by LostFishEU updated September 25, 2024
  • In-depth
5
27
Votes
22
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[14.18] Vayne guide by misterfirstblood

Guide by misterfirstblood updated September 15, 2024
7.6
17
Votes
6
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[14.16] The Ultimate Vayne ADC Guide *updated*

Guide by DJtheTiki updated August 21, 2024
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

SOLO CARRY Vayne top lane

Guide by WayB3tterThanYou updated July 16, 2024
7.1
10
Votes
4
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne complete guide

Guide by Aleexex updated June 23, 2024
7.3
17
Votes
7
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[ 14.12 ] Lethality / AD vayne

Guide by Xr3ad updated June 12, 2024
5.6
6
Votes
6
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

High Octane Vayne

Guide by Galaxima updated June 4, 2024
  • In-depth
9.8
856
Votes
71
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne, the On-Hit Menace (Patch 14.10)

Guide by ifound1dollar updated May 16, 2024
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

14.10 BROKEN FREE ELO CRITICS VAYNE

Guide by Shoro Mota updated May 24, 2024
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne - for every occasion - by s2 expert

Guide by Oakart updated April 28, 2024
  • In-depth
10
30
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[14.1] [Master] Leaf Vayne Guide - Season 14

Guide by Leaf no Kitsune updated January 15, 2024
8.7
9
Votes
0
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[14.1b] Mastering Vayne's On-Hit Build for Maximum Impact [READ NOTES]

Guide by Freezeey updated January 19, 2024
Season 14 Builds // Patch 14.21
New Guide
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

VAYNE TOP TANK

Build by Guest updated October 28, 2024
Season 14 Builds // Patch 14.20
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[Season 14.16] Vayne fast big damage!

Build by ChaseLombre updated October 14, 2024
Season 14 Builds // Other Patches
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

op bruiser vayne

Build by doomfallover updated October 3, 2024
  • Off-Meta
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Jesuscirraptor ADC The Fast

Build by Jesuscirraptor updated September 22, 2024
  • Off-Meta
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

One

Build by Guest updated September 10, 2024
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Jesuscirraptor SUP

Build by Jesuscirraptor updated August 7, 2024
  • Off-Meta
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Berserker Vayne

Build by Lycoris_Radiata updated August 1, 2024
  • Off-Meta
1 2 3 4 5 6 7 8 29 50
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