Flat AD, and or Armor Pen in your reds and quints is probably the way to go.
Flat armor yellows.
Flat armor yellows.

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This is perhaps a bit off topic to your question since I don't know much about runes, but I prefer to build him tanky + atmas impaler for some dps. This works well for the beginners who die a lot and once u get ur frozen mallet + warmogs, the atmas give u +82 dmg, if you add in a infinity edge, you'll end up with total of 300+ dmg late game and 43% critical hit with 4000+ hp. Hmm maybe I'll make a guide..
I capitalize on early game with full armor pen runes. Blues and yellows are a full armor(yellows) with a little bit of CDR in blues and MR/MR per lv blues(depends on the opponent)
Fast brutalizer for more Armor pen and get Phage->FroMal->Atmas
Throw in some MR item and you have yourself a build! Any HP item works well because of the Atmas. Spirit visage is great because of your passive and Garen uses all of the stats.
Fast brutalizer for more Armor pen and get Phage->FroMal->Atmas
Throw in some MR item and you have yourself a build! Any HP item works well because of the Atmas. Spirit visage is great because of your passive and Garen uses all of the stats.
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In high elo, Garen is not played because he sucks :)
And when he is, it's glass cannon.
And when he is, it's glass cannon.

http://www.mobafire.com/league-of-legends/build/duffs-336706
Come hang out when I'm streaming! http://www.twitch.tv/dufftime
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