Difficult, but Winnable with Patience
This matchup is extremely unfavorable for Vayne during the laning phase. Caitlyn controls the lane with her superior range, constant pressure, and zoning tools, making it hard for Vayne to farm or trade safely.
How to play against:
Accept that you’ll fall behind early. Your goal is to survive and scale, not win the lane.
Avoid direct trades. Only go in if she wastes cooldowns or if your support creates a clear opportunity.
Prioritize completing your early items quickly and use your recalls to return stronger and gradually regain lane control under pressure.
Use Tumble (Q) wisely — for farming, dodging poke, or repositioning safely.
Engage supports are ideal in this matchup. If you’re with an enchanter, play even more safely.
If she oversteps, that’s your only real chance — punish her with an all-in, especially early on.
Final Summary:
Don’t try to force plays. Vayne scales much better. Play calmly, minimize losses, and wait for your moment to shine in the mid/late game.
Draven
LEAGUE OF DRAVEN:
Draven is, without a doubt, one of the most oppressive ADCs in the early game — he wins nearly every trade and snowballs insanely hard off a single kill. His spinning axes provide constant, explosive damage, and his passive punishes even the smallest of mistakes.
How to play against:
Avoid early fights: You don’t win against him at any point during the laning phase without help. If you must fight, only do it if you’re full HP and have the numbers advantage.
Don’t let him get kills. The difference between a 0/0 Draven and a 1/0 Draven is massive. If he snowballs, the lane is basically over.
Play for farm: Focus on farming safely and keeping the game under control. If he’s not ahead in gold, you’re already doing well.
Trust your scaling: You’re way more useful than him in teamfights mid to late game.
Take smart resets: Close out your early items as soon as possible and come back stronger. Every good reset is a chance to breathe.
Punish mistakes: If Draven wastes his E or mispositions trying to catch an axe, go in with a well-timed E or a quick all-in using Q.
Recommended runes: Consider running Bone Plating to survive early trades.
Final Summary:
This lane is pure suffering if Draven knows what he’s doing. Don’t fight for free, play around your jungler, absorb the pressure, and focus on what Vayne does best — scaling. If you make it to mid game alive, then it’s your turn to shine.
Ashe
Ashe is a long-range champion with a lot of area control, which can make Vayne's early game difficult. Her constant poke, slows, and the ultimate that stuns can make the lane quite challenging, especially if she has a good support with CC. However, Vayne has the advantage of scaling better and becoming a significant threat in the mid and late game.
How to play against:
Be cautious with her R. If you're caught by Ashe's ultimate without having Cleanse, you're almost certain to die, especially if her support is nearby.
Don’t fight in the early levels. In the early stages, Ashe has an advantage with poke and lane control. Avoid trades and use your Q to gain small advantages and farm until level 6.
Focus on your spikes. With your first item, you start winning trades more easily, especially because of Vayne's mobility and damage.
Wait for the right moment. Once you get a good reset and have your ultimate, the matchup shifts in your favor. Ashe becomes more vulnerable after using her ultimate, making her easier to deal with.
Final summary:
Ashe is strong early, but Vayne scales better. Play patiently, avoid unnecessary fights early on, and take advantage of the right moment to turn the game around in the mid/late game, where Vayne shines much more.
Varus
Varus has the range and poke advantage, making this a tough matchup. He can deal serious damage with his Q and E, but the key to winning is dodging his skillshots and looking for all-in opportunities when he misses his abilities.
How to play against:
Avoid the poke. Varus’ Q can be deadly if it hits. Use your Q (Tumble) to dodge and stay safe.
Watch out for his ultimate. Varus' R is a huge threat. It not only roots you, but also prevents you from using your R invisibility and Q effectively. If you get caught, you’ll lose a lot of damage potential. Cleanse is a great option to remove the root and keep fighting.
Play patiently until level 6. Before level 6, Varus doesn’t have much all-in threat. Focus on farming and avoid unnecessary damage.
Bait his cooldowns. If Varus misses his Q, E, or R, you have a big window to engage. He relies heavily on his abilities, so take advantage when they’re down.
Look for short trades. When Varus overextends, punish him with an all-in. If he doesn’t have Blight stacks or misses a skill, you have a good chance to come out ahead.
Final Summary:
Varus is a high-range threat, but with patience, smart dodging, and Cleanse to remove his root, you can manage the lane. Avoid poke, scale safely to level 6, and punish his mistakes to turn the matchup in your favor.
Jinx
Jinx has a lot of range with her Q rockets, pushes the wave easily, and can punish you every time you try to farm. Her W deals good damage from afar, and her E can lock you down and guarantee an all-in. However, she has no mobility, which gives you room to abuse short trades.
How to play against:
Avoid long trades. Jinx can kite you easily in the early game. Use your Q to reposition and go for quick trades whenever she’s autoing minions.
Watch out for her E. If you get caught by her traps, the trade is over. Don’t walk in straight lines and keep an eye on her positioning.
Respect her range. She’ll poke with W and zone you with rockets. If she gets an early lead, she can snowball quickly.
Power spikes are your turning point. Once you complete your first item and reach level 6, the matchup gets much better. Her lack of mobility makes her vulnerable to any mistake.
Final Summary:
Annoying matchup early on, but totally winnable with patience and focus. Dodge her E, avoid free poke, use Q wisely to trade or escape, and punish any bad positioning from her.
Samira
Samira is an explosive champion with high all-in potential. She usually comes with strong engage supports.
How to play against:
Avoid the all-in. In the early levels, try to control the lane between level 1 and 2 by auto-attacking her whenever she goes for farm. But respect the engage — if she jumps in with her support, the trade can end immediately.
Wait for her W. Never use Condemn (E) before baiting out her W, which blocks projectiles. If you misuse E, you lose one of your only tools to stop her ultimate.
Use your range. Vayne has more range, so look for short trades with Q + AA whenever she goes for a last hit and her Q is on cooldown.
Spikes and Condemn. After your first item, fights become more favorable. Vayne’s E cancels Samira’s R, so save it especially for that moment.
Final Summary:
Avoid all-ins, abuse your range, and play patiently until you hit your spikes. Samira relies on engage and landing her full combo — if you deny that, the matchup can easily swing in your favor.
Lucian
Lucian is one of the strongest early-game champions, with high burst and extremely efficient short trades. He can punish any mistake you make in the first levels and completely dominate the lane.
How to play against:
Avoid short trades early on. His Q + auto attacks deal a lot of damage. If he gets 1 or 2 favorable trades, he’ll control the lane easily. Let him push the wave and play reactively.
Use your Q wisely. His Q goes through minions, so never stand in a straight line behind them when farming. Save your Tumble (Q) to dodge his Q—otherwise, you’ll be punished easily.
Never fight without your wave. If you try to force a trade without your minions around, Lucian can melt you with his ultimate uninterrupted. Only fight when you can use the wave to your advantage.
Condemn and cooldown tracking. Lucian’s E (dash) has a relatively low cooldown, so avoid using Condemn (E) if he can still escape. Try to save Condemn for moments when his dash is down or when he's near a wall.
Final Summary:
Tough early-game matchup, with a lot of pressure from Lucian. The key is patience: dodge his Q, use the wave smartly, don’t fall for short trade baits, and wait for your item spikes to turn the game around.
Kalista
Kalista is a marksman with unique mobility and a lot of early pressure. However, her range is the same as Vayne's, so you can go toe-to-toe if you know when to capitalize on the right moments.
How to play against:
Avoid long trades. Kalista's passive causes each auto attack to apply spears that are pulled with her E, dealing a lot of damage. So, never trade for too long — prefer short trades with Q+AA and retreat immediately.
Play around her farm. When Kalista goes for last hits, she gets briefly stuck in the jump animation, which gives you the opportunity to use Q forward and punish with an auto attack. Repeating this often will start to pressure her out of lane.
Dodge her Q. Her spear sets up for her E, so always try to use your Q defensively if you see she's about to engage. Dodging her Q delays the damage she can apply during trades.
Be cautious at level 6. Kalista's ultimate enables very aggressive plays with her support. If she’s paired with a strong engage support (like Nautilus or Alistar), respect this combo even more and keep your wave in a safe position.
Item spike is key. Kalista doesn't scale as well as Vayne, so if you survive the early game, the match naturally becomes easier.
Final Summary:
A volatile matchup early on, with lots of pressure from Kalista. The key is: avoid long trades, play around her farm, use your Q effectively, and don't expose yourself to a level 6 all-in. If you survive the laning phase without dying, Vayne scales and dominates easily.
Tristana
Tristana is a marksman with high burst potential, especially in the early game, with her combo of E (Explosive Charge) and quick auto attacks.
How to play against:
Avoid her all-in. If Tristana jumps on you with E and lands 4 auto attacks, you will likely die.
Use Condemn (E) to cancel her jump and buy time.
Play safely and use your Q to punish her last hitting.
Focus on farming. Avoid short trades when her E is up and use your range advantage to farm safely.
Final Summary:
The key is to avoid her all-in, play safely, and use Condemn at the right time. If you survive her burst, Vayne will scale better and take control later.
Aphelios
Aphelios is a very versatile marksman and can be tricky for Vayne due to his superior range, constant poke, and higher combat damage with his weapon rotation. However, Vayne can gain the advantage if she knows how to manipulate Aphelios's abilities and find the right moments to engage.
How to play against:
Play aggressively or defensively depending on your support. If you have a good support, try to pressure Aphelios; if not, play more defensively.
Avoid the all-in early. Aphelios has more range and considerable poke, so wait until he uses his abilities.
Bait his abilities. Aphelios is more vulnerable when he doesn't have abilities available. If he makes a mistake, try to engage with everything.
Control the wave. If he has more range, let him push the wave to you and wait for level 3 to start fighting back.
Final Summary:
Aphelios can be a difficult matchup due to his poke and damage, but with patience and proper use of abilities, Vayne can survive and turn the game around. The key is to avoid long trades, wait for the right moment to engage, and take advantage when Aphelios is without his abilities.
Nilah
Nilah is a melee champion with a kit fully focused on all-ins. She gains bonus experience through her Q, so if she gets an early lead, she can snowball incredibly fast.
How to play against:
Abuse your range. In the early levels, you're stronger. Use this to control the lane, deny her CS, and poke her every time she walks up for minions.
Watch her level 3. From level 3 onwards, Nilah can look for dangerous all-ins. Never fight her head-on if her cooldowns are up. Use your Q for spacing and E (Condemn) to interrupt her engage.
Play around her W. Her ability to block projectiles is Nilah’s biggest threat. If she wastes it, you have a huge window to punish her. The cooldown is long, so always look to trade around that.
Don’t fall behind in XP. Nilah’s bonus experience allows her to level up faster. If she starts getting lane priority, she’ll likely hit level 6 way before you and force an unwinnable fight.
Final Summary:
The lane gets hard if she gets an early lead. Play to deny her farm, control the wave, and abuse your range advantage. If you keep the pressure up and hold onto Condemn to stop her all-ins, you’ll scale and take over the game with ease.
Ezreal
Ezreal can be a small threat if you know how to control the wave and play patiently. He has good range and poke, but doesn't have much burst potential, so you can win most 1v1s if you play smart.
How to play against:
Focus on farming: The main advantage against Ezreal is controlling the wave. He tends to stay back and focus on farming with his Q, allowing you to farm safely. Use this to scale.
Dodge the poke: Ezreal will try to poke with Q from afar. Stay alert and dodge his abilities to avoid losing too much health.
Control the wave: Avoid being pushed to your tower. By keeping the minion wave in a favorable position, you limit the space Ezreal has to poke you safely.
Punish mistakes: If Ezreal misuses his E (Arcane Shift), take the opportunity to engage. He is vulnerable when he doesn't have this ability available.
Final Summary:
The key to beating Ezreal is controlling the wave and playing safely, without letting him poke you. If you're patient and execute well, you’ll scale faster and be able to dominate later. The matchup is easier if you can maintain pressure and punish his mistakes.
Kai'Sa
Kai’Sa can be a fairly even matchup for Vayne, but it requires attention to detail. She has considerable burst damage when you're isolated, especially with her Q and passive. In addition, her W can reveal you even while you're using Vayne's R (stealth), which is dangerous. Still, Vayne has the tools to deal with her if played correctly.
How to play against:
Avoid being isolated. Most of Kai’Sa’s damage comes from her Q when there are no other nearby targets. Always fight near your wave or with your support close by.
Dodge the W. Her W reveals your location even during your ultimate. If she hits it, she can all-in with R and burst you down.
Play around minions. Staying inside the wave helps split the Q damage and blocks the W, greatly reducing her burst potential.
Use Condemn well. If you can knock her into a wall with E, the trade will likely go in your favor. Look for this especially in 1v1s.
Be patient early. Kai’Sa has slightly stronger trades early on, so focus on farming and avoid giving her an advantage.
Final Summary:
Even matchup. Kai’Sa has a slightly better early game, but if you play around the wave and avoid being isolated, Vayne scales better and can take over later on. The key is to deny her burst and punish her mistakes.
Miss Fortune
Miss Fortune currently has a very safe early game and an even more stable mid game, thanks to her itemization that offers protection and sustain. She can stay out of danger and deal a lot of damage from range, making direct trades difficult. However, Vayne can abuse her own mobility and ultimate to go invisible and catch her off guard, creating good all-in opportunities. But be careful — if MF gets too far ahead, her critical damage and sustain become terrifyingly strong, and she can burst you down before you even react.
How to play against:
Avoid Q ricochets. Never stand behind low-health minions or she’ll poke you for free.
Watch out for her E. MF’s slow can leave you exposed to her ultimate. If you get caught like that, your chances of surviving are slim, especially if her support has CC.
Use Condemn (E) to cancel her ult. If she uses her ultimate and you’re in position, use E to knock her back and interrupt the channel.
Play around cooldowns. MF relies heavily on abilities for damage. If you bait her W or ult, she becomes much more vulnerable.
Level 6 is your power spike. Once you get your ultimate, you can use Vayne’s mobility to all-in, especially if you can land a wall Condemn.
Final Summary:
Even matchup, but she has strong pressure in early and mid game. Avoid poke, play around minions, and use your ultimate to surprise her. If Miss Fortune gets ahead, respect her damage and look for fights with your team or in favorable situations.
Jhin
Jhin can be an even matchup for Vayne, but it requires some important early-game precautions. He has a strong burst and can pressure very well in the early game, especially if you get hit by his fourth shot or caught by a skillshot combo. However, he has clear vulnerabilities that Vayne can exploit, especially as the game progresses.
How to play against:
Avoid the 4th shot. Jhin's fourth autoattack deals a lot of damage. Play around this and respect it, especially in the early levels.
Dodge his abilities. Use your Q (Tumble) to dodge his W and avoid the poke from his Q. If you manage to do this consistently, he loses much of his lane impact.
Take advantage of reloads. When Jhin is reloading, he becomes extremely vulnerable. Use this opportunity to go in with an auto + Q and back off, or force a longer trade if you have the advantage.
Be careful with all-ins in front of his turret. If he hits you with his W and opens his R, he can quickly finish you off. Avoid trades in unfavorable terrain.
Use E (Condemn) to cancel his R. If he uses his ultimate and you're in position, push him with your E to interrupt it.
Final Summary:
The matchup is manageable if you respect the early game and play around his reloads and the 4th shot. After level 6 and with your first item, Vayne starts to dominate the trades. With two items, Jhin will struggle to win a 1v1. Be patient, play cleanly, and take advantage of the openings he gives you.
Kog'Maw
Kog'Maw can be a difficult matchup, especially if he has support, but Vayne can control him with patience and good decisions. The key is to avoid trades when his W (Bio-Arcane Barrage) is active, as he has much more damage and range.
How to play against:
Bait the W: When Kog'Maw's W is on cooldown, he becomes vulnerable. Take advantage of this moment to trade.
Disengage if W is active: Stay out of range and don't try to fight when his W is in use.
Pressure after the W cooldown: Once his W is over, look for trades.
Final Summary:
Kog'Maw can be dangerous, but if you control the timing of his cooldowns, you can easily win trades. Be patient and take advantage of when his W is off cooldown.
Sivir
Sivir is an easy matchup for Vayne, but it requires caution with her Q and W. She has a good poke ability, but Vayne can leverage her mobility to make favorable trades. At level 6, you can easily go for an all-in and win the duel.
How to play against:
Avoid the Q: Sivir's Q deals significant damage. Try to dodge it to avoid losing too much health.
Watch out for the W: Sivir's W can block your E (Condemn). Don't try to use E if she has W available.
Play around her cooldowns: Sivir has strong waveclear, but her abilities have long cooldowns. Use that time to take short trades.
All-in at level 6: When you hit level 6 and have your ultimate, you can easily engage and defeat Sivir in an all-in.
Final Summary:
This is an easy matchup for Vayne. The key is to avoid her Q poke, play around her cooldowns, and use your mobility to force favorable trades. Once you have your ultimate, engage and win without much trouble.
Twitch
Twitch is an even matchup against Vayne, where the key is to play safely, especially in the early levels. He doesn't have many direct threats, but his attack speed boost when he exits stealth can be problematic.
How to play against:
Avoid early trades. At the start, Vayne doesn't beat Twitch until level 3.
Play around his stealth. Be aware of his attack speed boost when he exits stealth and avoid being caught off guard.
Manage the wave. Control the wave well and let your support help in the lane.
Exhaust in duels. Use Exhaust to reduce his damage, and if possible, Condemn to control him.
Capitalize on his mistakes. Twitch has high cooldowns on his abilities; use that to your advantage after he misses a poke or ability.
Avoid his R. If he tries to use his R, be quick with your Q or Flash to avoid his auto attacks.
Final Summary:
This matchup is 50/50, depending on who takes the early lead. Vayne can win with good wave management and using Exhaust in duels, as Twitch is vulnerable to Vayne's mobility and has high cooldowns on his abilities.
Xayah
Xayah is a challenging matchup for Vayne due to her range and control with feathers. She can deal significant burst damage with her E, and her ultimate can make trades harder.
How to Play Against:
Avoid running in a straight line, as she can root you.
Pay attention to the feathers and use your Q to move away from them.
Bait her ultimate and have your Flash ready to escape.
Early on, she is stronger, but you gain the advantage in the mid game.
Bait her Q and E to look for favorable trades or all-ins.
Final Summary:
If you can avoid Xayah's abilities and bait her ultimate, you can win trades, especially in the mid game. Respect the feathers and use your mobility to your advantage.
Zeri
Zeri is an easy matchup for Vayne, especially if you play with patience. Take advantage of wave control and make short trades. Use Condemn to stop her E when she tries to escape using the wall.
How to play against:
Stay behind minions: This makes it harder for Zeri to land her abilities on you.
Use Q and E: Poke Zeri whenever she tries to farm, especially if she uses E to escape. Condemn her into the wall.
Escape cancellation: If Zeri tries to use R or escape with E, use Condemn to disengage or immobilize her against the wall.
Take advantage of the early game: You have an advantage early, so use that to apply damage and control the lane.
Final Summary:
This is a straightforward matchup. With good wave management and smart use of Condemn, Vayne has a clear advantage against Zeri.
Corki
Corki has good waveclear and scaling, but Vayne can defeat him after the early game by taking advantage of Corki's ability cooldown windows, especially the E (Package).
How to play against:
Safe Farming: Focus on farming and avoid trades until level 6.
E Cooldown: Take advantage of when Corki uses his E to force trades.
Scaling: After the first item, Vayne gains a slight advantage, but be cautious of Corki's power spike with his second item.
Long Trades: Use your mobility to dodge and kite Corki.
Final Summary:
In the early game, Corki is strong, but Vayne gains an advantage after acquiring her items. Play with patience, take advantage of Corki's cooldowns, and dominate in the mid/late game.
Smolder
Smolder free lane !
How to play against:
Farm Safely: Focus on farming and avoid trades until you complete your first item.
Avoid the Poke: Be careful with Smolder's range and abilities.
Final Summary:
The lane is easy for Vayne if you focus on farming and avoiding Smolder's poke. After completing the first item, you begin to dominate the matchup.
Lulu
Lulu is the best duo for Vayne, especially with the Phantom Dancer build. Her ability to provide protection, movement speed, and attack speed bonuses greatly improves Vayne's performance in fights.
Karma
Karma will help you a lot in the laning phase by applying pressure on the enemy and allowing you to farm peacefully.
Nami
Nami provides solid sustain in lane and great disengage in teamfights with her ultimate and crowd control abilities.
Janna
Janna provides great disengage and peel, allowing Vayne to play more freely in fights. Her shield boosts your damage, and the tornado helps control enemy engages. The bonus mobility from her passive also synergizes very well with Vayne’s playstyle.
Nautilus
Nautilus has a strong engage and allows you to play aggressively early on, creating opportunities to catch enemies off guard.
Yuumi
Meow
Renata Glasc
Acceptable.
Thresh
Thresh is an excellent support overall. He provides great map control with his lantern, allowing him to save allies and start fights with his Q (Death Sentence). His passive, combined with the ability to hook and the peel from his ultimate, provides immense utility to the team. Thresh can also secure important picks and turn the game around with well-timed lanterns.
Tahm Kench
Although not picked often, I really enjoy playing him. A well-played Tahm Kench will make you happy at any moment, with his potential to save allies and create unexpected plays.
Rell
rell is a great support focused on crowd control and engage.
Milio
Milio provides decent healing and, while not the strongest in sustain, gains a lot of range to pressure the lane.
Alistar
Acceptable.
Senna
Acceptable.
Leona
Acceptable.
Braum
Acceptable.
Soraka
Acceptable.
Sona
Acceptable.
Rakan
Acceptable.
Blitzcrank
Acceptable.
Zilean
Acceptable.
Vel'Koz
Swain
Xerath
Zyra
Ashe
Lux
Brand
Pyke
Bard
Synergies
IdealStrongOkLowNone
Lulu
Lulu is the best duo for Vayne, especially with the Phantom Dancer build. Her ability to provide protection, movement speed, and attack speed bonuses greatly improves Vayne's performance in fights.
Karma
Karma will help you a lot in the laning phase by applying pressure on the enemy and allowing you to farm peacefully.
Nami
Nami provides solid sustain in lane and great disengage in teamfights with her ultimate and crowd control abilities.
Janna
Janna provides great disengage and peel, allowing Vayne to play more freely in fights. Her shield boosts your damage, and the tornado helps control enemy engages. The bonus mobility from her passive also synergizes very well with Vayne’s playstyle.
Nautilus
Nautilus has a strong engage and allows you to play aggressively early on, creating opportunities to catch enemies off guard.
Yuumi
Meow
Renata Glasc
Acceptable.
Thresh
Thresh is an excellent support overall. He provides great map control with his lantern, allowing him to save allies and start fights with his Q (Death Sentence). His passive, combined with the ability to hook and the peel from his ultimate, provides immense utility to the team. Thresh can also secure important picks and turn the game around with well-timed lanterns.
Tahm Kench
Although not picked often, I really enjoy playing him. A well-played Tahm Kench will make you happy at any moment, with his potential to save allies and create unexpected plays.
Rell
rell is a great support focused on crowd control and engage.
Milio
Milio provides decent healing and, while not the strongest in sustain, gains a lot of range to pressure the lane.
I’ll try to keep this guide updated, add new information, and create guides for other champions in the future. I hope this guide helps you in some way!
Overall, the goal is to get Experimental Hexplate as quickly as possible to combo with your ultimate. Considering the gold-to-stat value, it’s the best item, plus it reduces your ultimate cooldown. Always focus on fighting when your ultimate is available and enjoy the performance of it to the fullest.
The build with Phantom Dancer is my favorite because it allows you to hit 3.00 attack speed with just three items, if you have some peel support. However, you’ll be very vulnerable until you get your defensive items, so just be careful with that and enjoy the game!
Items
First Core Item – What to Build and Why
Blade of the Ruined King is ideal for Vayne due to its synergy with basic attacks and on-hit effects. The bonus damage based on the enemy's current health allows her to melt tanks and high-HP champions. Additionally, the lifesteal and attack speed boost her sustain and consistent damage. The passive slow effect helps her kite, letting Vayne keep her distance from melee threats.
While Blade of the Ruined King is effective against high-health targets, it can be less impactful against enemy comps full of squishy, long-range champions. In such cases, other items might be a better option.
Statikk Shiv is a situational pick for Vayne when your team lacks wave clear. Since Vayne struggles to quickly clear waves, this item helps significantly in that regard, allowing her to hold the lane alone when the support is roaming or playing weakside. The item's passive enables her to clear minions efficiently, improving her lane control and overall game tempo. It’s ideal in compositions without wave clear or when the support spends a lot of time away from the lane.
Kraken Slayer is an excellent choice when you need an early power spike in the game. Against squishy champions or in matchups where you can farm and trade safely, the item offers strong and consistent damage from the start. It allows Vayne to apply pressure earlier and capitalize on small advantages.
Although it's not ideal against extremely tanky compositions, Kraken shines in games where you don’t need percent-health damage and want to have an earlier impact in fights.
Yun Tal Wildarrows functions as a modern lethality alternative for Vayne. It’s excellent for deleting fragile champions and enemy carries with ease, offering a strong damage spike during the early and mid game.
This build is a powerful choice when you want to make an early impact and play aggressively, taking advantage of the high burst damage it provides.
However, it’s not ideal for the late game and struggles against tanky champions or heavy armor builds, where percentage-health damage builds tend to perform better.
Second Core Item – What to Build and Why
Guinsoo's Rageblade has become the go-to second item for Vayne due to its strong synergy with her kit. Its passive grants up to 32% bonus attack speed, which helps Vayne trigger her W (Silver Bolts) much faster, increasing her sustained damage in extended fights. Once fully stacked, every third auto attack applies on-hit effects twice, which massively boosts her W damage and allows her to melt even the tankiest targets with ease.
This combination of bonus attack speed and enhanced on-hit effects fits Vayne’s playstyle perfectly, since she thrives on rapid auto attacks and triggering her W (Silver Bolts) as often as possible. That’s why, unless you’re going for a split push setup with Trinity Force or a crit-focused build with Infinity Edge, Guinsoo remains the most consistent and powerful second item to maximize her damage output.
Infinity Edge is only a core item when you're committing to a full crit build — for example, starting with an item like Yun Tal Wildarrows and then picking up Infinity Edge as your second item. It significantly boosts your critical strike damage and offers a high amount of AD, making it perfect for the crit-oriented playstyle that focuses on bursting down squishy targets quickly and efficiently.
Trinity Force is a very flexible item and is commonly built in Vayne top lane builds focused on split pushing and poking with empowered Qs. However, it can also be a viable option in the bot lane, especially against burst or assassin-heavy comps that can quickly delete you. While it offers less consistent DPS compared to other builds, it provides strong burst damage through Q trades and a more mobile, survivable playstyle overall.
Wit's End as an example because it’s one of the best “flex” or “wild card” items for Vayne — it gives you both attack speed and magic resistance, making it a great defensive option. It’s especially strong as a second item when facing a full AP enemy or a heavy magic damage threat. The same logic applies if you're against a full AD comp, where you’d consider defensive items like Randuin's or Shieldbow. But unless you really need that extra survivability, it's almost always better to stick with Guinsoo’s Rageblade as your second item to maximize damage and synergy with Vayne’s kit.
Abilities
WARN !WARN !WARN !
skill guide for beginners, if you have knowledge about vayne ignore this topic
Night Hunter (Passive): gains 30 bonus movement speed while facing a nearby visible enemy champion, increased to 90 while under the effects of ability Final Hour.
Tumble (Q) VayneTumble, maneuvering to carefully place her next shot. She rolls toward the cursor and her next attack deals 75 / 85 / 95 / 105 / 115% (+50% of ability power) bonus physical damage. This bonus damage is not increased if the attack critically strikes.
Silver Bolts (W) Vayne tips her bolts with a rare metal, toxic to evil things. The third consecutive attack or ability against the same target will deal 6 / 7 / 8 / 9 / 10% of the target's maximum health as bonus true damage (Max damage vs. monsters is capped at 200).
Condemn (E) Vayne draws a heavy crossbow from her back, and fires a huge bolt at her target, dealing 50 / 85 / 120 / 155 / 190 (+0.5 per bonus attack damage) physical damage and knocking them back (900 units). If they collide with terrain, they are impaled, dealing 150% of Condemn's initial damage again and stunning them for 1.5 seconds.
Final Hour (R) Vayne gains 35 / 50 / 65 attack damage for 8 / 10 / 12 seconds, extended by 4 seconds whenever a champion damaged by Vayne dies within 3 seconds. Additionally, during the duration, Night Hunter instead grants 90 movement speed. The cooldown of Tumble is reduced by 30 / 40 / 50%, and grants invisibility for 1 second.
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