Hi! I'm
ifound1dollar, a
Diamond
Vayne main in North America (spoiler: this isn't a
Vayne guide). I have decent experience on
Twitch, so I decided to make an in-depth guide for him!
This is my in-depth guide to
Twitch. I hope you learn a thing or two!
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This is the standard ability sequence for
Twitch. You'll want to start off with a point in
Contaminate, as it can help with farming and level 1 trades. Level 2 you should get a point in
Venom Cask, as the slow and passive stacks can mean the difference between winning or losing a level 2 trade/all-in.
Ambush should be taken at level 3.
Contaminate should always be maxed first, as it's damage increases a lot per rank, and should be followed by maxing
Ambush for the increased
Camouflage duration and
Attack Speed. A point in
Spray and Pray should be taken at levels 6, 11, and 16.
Venom Cask should be maxed last, as it only increases the slow and decreases the cool-down.
Passive: Deadly Venom
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Cost: None
Cooldown: None
Range: Self
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Twitch's basic attacks infect the target, dealing 1/2/3/4/5 (+3% Ability Power) True Damage every second for 6 seconds, stacking up to 6 times. The amount is increased every 4 levels.
Twitch's passive is an important part of his kit, as Ambush's reset, Contaminate's damage, and Venom Cask rely on it. It may not deal much damage early game, but late game, 30 True Damage every second definitely adds up.
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Q: Ambush
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Cost: 40 Mana
Cooldown: 16s
Range: Self
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After 1.5 seconds, Twitch becomes Camouflaged for 10/11/12/13/14 seconds. While Camouflaged, Twitch gains 10% bonus Movement Speed. If Twitch attacks an enemy unit while Camouflaged, he gains 30/35/40/45/50% bonus Attack Speed for 5 seconds.
Ambush's cool-down is reset when an enemy effected by Deadly Venom dies.
If Twitch takes any damage while casting Ambush, the activation is delayed to 4.5 seconds.
Twitch gains 30% bonus Movement Speed when near an enemy that can't see him.
Ambush is an important part of Twitch's kit, as he relies on it to safely reach the enemy back line and blow them up. The bonus Attack Speed it grants is also a huge part of the ability's effectiveness, as it increases his DPS by quite a bit.
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W: Venom Cask
E: Contaminate
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Cost: 50/60/70/80/90 Mana
Cooldown: 12/11/10/9/8s
Range: 1200
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Deals 20/30/40/50/60 Physical Damage to enemies effected by Deadly Venom. It deals an additional 15/20/25/30/35 (+.35 per bonus Attack Damage) Physical Damage and (+33% Ability Power) Magic Damage per stack of Deadly Venom on them.
This is Twitch's only directly damaging ability, and is a very important execution tool since the damage increases per Deadly Venom stack. This does decent damage in the early game, but eventually deals massive AOE damage come late game thanks to Spray and Pray and Runaan's Hurricane. When trading in lane, it's important to save this ability until the last possible moment, because it's damage scales per stack of Deadly Venom and has incredibly long range.
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R: Spray and Pray
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Cost: 100 Mana
Cooldown: 120/110/100s
Range: 850
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For 5 seconds, Twitch gains 300 attack range, 20/30/40 bonus Attack Damage, and his attacks become piercing bolts that deal 5% less damage to subsequent targets, down to a minimum of 70%.
Twitch's ult is why he's such a strong late game champion; it deals AOE damage to all targets in an area that can Critically Strike. Late game, when combined with high Crit chance and Attack Damage, this ability's bonus AD and range allows Twitch to 3-shot the entire enemy back line from a long distance. Because you'll be attacking from so far away and so quickly, the enemy team will have a hard time jumping on you before you tear them to shreds, which is why Twitch is such a huge threat late game.
Tip: You can activate Spray and Pray while Camouflaged from Ambush, and you won't be revealed. This can catch enemies off guard, as the ability will have already been activated before you begin to DPS. Use this to your advantage.
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RUNE STATS
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OFFENSE
+10% Attack Speed
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FLEX
+9 Adaptive Force (5.4 AD)
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DEFENSE
+6 Armor or +8 Magic Resist
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PRIMARY TREE
PRECISION
Press the Attack
Press the Attack deals bonus adaptive damage to an enemy champion after auto attacking them 3 times, and increases the damage they take for a period of time after. Being that
Twitch's damage is primarily through auto attacks, this synergizes very well with him. However,
Fleet Footwork can be another option;
Twitch has a weak laning phase, so the sustain from this rune can help him survive with the cost of less late game damage.
Lethal Tempo isn't a great option because the bonus
Attack Speed only applies after a delay, and by that time,
Twitch may easily have already wiped the enemy team or been killed.
Conqueror is a rune best designed for bruisers, and therefore doesn't really work well with
Twitch.
Triumph
Triumph heals you for 12% of your current
Health and grants 20 bonus gold on a takedown. This can mean the difference between life and death in skirmishes and teamfights, so it's always a safe option. However,
Overheal is another option, because can be useful when running
Fleet Footwork or when paired with a healing support like
Soraka.
Presence of Mind is a poor option, as most attack-based marksmen don't rely on
Mana.
Legend: Alacrity
Coup de Grace
Coup de Grace is a very well-rounded, consistent option for basically any carry, since it deals bonus damage to enemies below 40%
Health. However,
Cut Down is definitely a viable option when facing heavy tank compositions.
Last Stand isn't a great option because as a marksman, you shouldn't rely on being low
Health to deal more damage.
SECONDARY TREE
INSPIRATION
Magical Footwear
Magical Footwear grants free boots after 12 minutes (reduced by 45s per takedown), and grants a bonus 10
Movement Speed. This is a safe option for any champion who isn't running
Predator, as a free 300g item is always beneficial. However,
Perfect Timing can also be a good option. It can help defend against and pull off dives, or negate a champion like
Talon's burst.
Hextech Flashtraption is designed for playmaking champions, and won't have much use for a marksman.
Biscuit Delivery
Biscuit Delivery grants 3
Total Biscuit of Everlasting Will that heal for 10% of you missing health, which is an incredibly useful tool for any marksman with a weak laning phase. Though
Future's Market can help to hit powerspikes earlier, it's really not worth paying the lending fee, so it's not a good option.
Minion Dematerializer is only viable on certain champions with specific playstyles, and attack-based marksmen aren't any of them.
Cosmic Insight
The third
Inspiration tree is a little lackluster for
Twitch. While
Cosmic Insight can be slightly beneficial because of the reduced
Summoner Spell cooldowns, it's really not a great option for an attack-based marksman.
Approach Velocity is basically useless, because you won't benefit much from moving faster towards movement impaired units as a marksman.
Time Warp Tonic is another rune that's designed for certain champions and playstyles, and doesn't do much for
Twitch.
SORCERY
 Details
Nullifying Orb
Nullifying Orb can really help when facing poke supports and/or heavy Magic Damage comps. It provides a Magic Damage shield when you fall below a Health threshold, which can mean the difference between life and death. Nimbus Cloak can make kiting a little easier, but Nullifying Orb is usually a safer bet. Manaflow Band doesn't really have any use on Twitch because as an attack-based marksman, he doesn't rely on Mana.
Celerity
Celerity causes Movement Speed bonuses to be 7% more effective on you (and gain 1% total Movement Speed). This can be useful for Twitch, as it does synergize with Ambush, but it's not very consistent. Absolute Focus isn't a good option, as it's very inconsistent. Transcendence isn't viable because Twitch doesn't rely much on CDR.
Gathering Storm
Gathering Storm is crucial for any late game carry. It grants infinitely stacking adaptive stats, and becomes very strong after 30 minutes. Scorch isn't very useful on Twitch because it's designed for champions that poke with abilities. Waterwalking is a very underwhelming rune and shouldn't be taken.
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ITEMS WIP
Crit Build:
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Blade of the Ruined King should always be your first item. It's incredibly efficient; it makes his laning phase much more bearable and scales incredibly well into the late game. It has great stats, and the Life Steal it grants really helps with sustain both in and out of lane. The most important part of the item, though, are it's active and passive. The active deals 100 Magic Damage to an enemy champion and steals 25% Movement Speed, which is a good bit of burst and helps with kiting. The passive causes auto attacks to deal 8% of the target's current Health as bonus Physical Damage, which absolutely melts enemies like Darius or Sejuani who stack Health.
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Runaan's Hurricane should be your first Crit item, as it synergizes very well with Twitch. It's passive allows him to deal Spray and Pray's damage and apply Deadly Venom to multiple targets simultaneously, and also helps him wave clear. Plus, as a Crit-based marksman, he needs to get Critical Strike chance as soon as possible. After finishing this item and Blade of the Ruined King, Twitch finally begins to deal a lot of damage.
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Your third item should be Infinity Edge. It's a vital part of any Crit champion's build because of the 80 Attack Damage and 25% Critical Strike chance it grants, as well as it's passive. It causes Critical Strikes to deal 225% damage instead of 200%, which is an enormous powerspike for any Crit champion.
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Your next item should be your third Crit item. It'll bring you to 75% Critical Strike chance, meaning you'll Crit on 3/4 auto attacks. Since this is the point in the game when you'll need to shred the enemy team, you'll need to Crit as often as possible. Realistically, though, you can choose any of the 3 remaining Zeal items: Phantom Dancer for more survivability, Statikk Shiv for more waveclear and burst, or Rapid Firecannon for bonus range.
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Your final item should always reflect the enemy team's composition. For example, if they're all building armor, you should purchase a Lord Dominik's Regards or even a Mortal Reminder if you need healing reduction. Without a Last Whisper item, you could wind up being unable to kill the enemy front line and lose the game as a result. However, if you're concerned about survivability, you should get a Guardian Angel for the Armor and revive, or a Maw of Malmortius to negate Magic Damage burst. But, if by some chance, you don't need to build defensively at all, you can instead buy Stormrazor or third Zeal item for 100% Critical Strike chance.
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The majority of the time, you'll want to pick up a Berserker's Greaves when playing Twitch. It's among the most efficient items in the game; it grants 35% Attack Speed and 45 bonus Movement Speed for only 1100g (or 800g with Magical Footwear), so there's not usually a compelling reason to get any other boots. However, if the enemy team is full AD and you're having a lot of trouble surviving, a Ninja Tabi can be sometimes be an effective option, but this is very seldom the case.
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I'm extremely greatful for jhoijhoi's
Making A Guide, because without it, I wouldn't have been able to create this guide.
If you liked the guide, feel free to vote and/or leave a comment or suggestion!
Feel free to check out my other guides:
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November 11, 2020 (Patch 10.23)

Spoiler: Click to view
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- Updated item build (preseason changes)
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- Updated 'Abilities' chapter (AP ratios on Passive, W, and E)
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September 2, 2020

Spoiler: Click to view
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- Updated 'Abilities' chapter
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April 30, 2020

Spoiler: Click to view
April 30, 2020

Spoiler: Click to view
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- Rewrote 'Pros/Cons' chapter
- Rewrote 'Abilities' chapter
- Rewrote 'Runes' chapter
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- Rewrote 'Items' chapter
- Updated Item build and Runes
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November 20, 2019

Spoiler: Click to view
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- Updated item build
- Updated 'Items' chapter
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June 4, 2019

Spoiler: Click to view
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- Redesigned 'Abilities' chapter
- Adjusted hyperlinks
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- Redesigned 'Runes' chapter
- Adjusted 'Pros/Cons' chapter
- Updated Rune information
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February 6, 2019

Spoiler: Click to view
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- Updated "Items" chapter
- Updated Item build
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January 24, 2019

Spoiler: Click to view
January 9, 2019

Spoiler: Click to view
December 4, 2018

Spoiler: Click to view
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- Created Guide
- Added 'Introduction' chapter
- Added 'Runes' chapter
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- Added 'Pros/Cons' chapter
- Added 'Abilities' chapter
- Added 'Items' chapter
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