You ignore the little lizards until you're finished with the Golem. They don't do enough damage to warrant killing them over the Golem, so in order to shed as much damage from yourself as possible, kill the Golem ASAP. If you can, have a teammate leash him to shed even more damage from yourself. After the main damage source (golem or elder lizard for red) are dead, kill the little guys.
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When starting at the Ancient Golem, what is one supposed to do about the little lizards?