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Recommended Items
Runes:
Precision
Domination
+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+65 Base Health
Spells:
Standard
Barrier
Flash
Items
Ability Order Standard
Deadly Venom (PASSIVE)
Twitch Passive Ability
Threats & Synergies
Extreme
Major
Even
Minor
Tiny
None
Low
Ok
Strong
Ideal
Draven
Lulu
outstandingly the best support
Ideal
Strong
Ok
Low
None
Lulu
outstandingly the best support
Champion Build Guide
Introduction
Hello everyone, I'm MisterFirstBlood from EUW, and today I'm excited to guide you through mastering
Twitch.
Twitch is an incredibly sneaky and deadly AD carry, known for his ability to ambush enemies and melt them down with his high DPS and poison. Whether you're new to
Twitch or looking to refine your skills, this guide will provide you with the knowledge and strategies you need to dominate the Rift. We'll cover runes, item builds, combos, and essential gameplay tips to help you maximize your potential with this powerful champion. Let's dive in and unleash the true power of
Twitch together!




Pro's and con's
Pros:
+ You can perform sneaky plays with his camouflage.
+ You can win teamfights alone; amazing late game.
+ Attack speed and damage buffs on Q and R push his damage over the top.
+ You can totally snowball a game when you get a lead.
+ Amazing teamfight-winning AoE hyper carry.
Cons:
- Easy to gank.
- Weak early game.
- No mobility except movement speed.
+ You can perform sneaky plays with his camouflage.
+ You can win teamfights alone; amazing late game.
+ Attack speed and damage buffs on Q and R push his damage over the top.
+ You can totally snowball a game when you get a lead.
+ Amazing teamfight-winning AoE hyper carry.
Cons:
- Easy to gank.
- Weak early game.
- No mobility except movement speed.
Abilities
Passive:
Deadly Venom
Twitch's basic attacks infect the target, dealing true damage each second.
Q:
Ambush
Twitch becomes Camouflaged for a short duration and gains Move Speed. When leaving Camouflage, Twitch gains Attack Speed for a short duration. When an enemy champion with Deadly Venom dies, Ambush's cooldown is reset.
W:
Venom Cask
Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.
E :
Contaminate
Twitch wreaks further havoc on poisoned enemies with a blast of his vile diseases.
R:
Spray and Pray
Twitch unleashes the full power of his crossbow, shooting bolts over a great distance that pierce all enemies caught in their path.

Twitch's basic attacks infect the target, dealing true damage each second.
Q:

Twitch becomes Camouflaged for a short duration and gains Move Speed. When leaving Camouflage, Twitch gains Attack Speed for a short duration. When an enemy champion with Deadly Venom dies, Ambush's cooldown is reset.
W:

Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.
E :

Twitch wreaks further havoc on poisoned enemies with a blast of his vile diseases.
R:

Twitch unleashes the full power of his crossbow, shooting bolts over a great distance that pierce all enemies caught in their path.
Items
Your first item to rush should always be
The Collector, followed by
Runaan's Hurricane.
The Collector synergizes well with your damage-over-time abilities and can secure additional kills.
Berserker's Greaves are your go-to when it comes to boots. The next best items to round out your damage core are
Infinity Edge and
Lord Dominik's Regards.
After finishing these, you should already have massive DPS output. Your next item choice should depend on your current needs in that specific game.
Bloodthirster,
Wit's End, and
Mercurial Scimitar are more defensive choices, with
Bloodthirster also offering a ton of AD.
That's pretty much all the relevant items in my opinion.






After finishing these, you should already have massive DPS output. Your next item choice should depend on your current needs in that specific game.




That's pretty much all the relevant items in my opinion.
Runes






In the




Tips
Play sneaky. Always try to punish unwary enemies, steal buffs, deny recalls, or even secure kills.
Join fights from an unseen spot or flank.
Your Q doesn't make you invisible; it's just camouflage. Nearby enemies will still be able to see you, so try to play around that radius.
Use W first to get additional poison stacks on your enemies, and as soon as you can't attack anymore, press E to maximize the damage.
Every time you get a kill or assist, your Q cooldown is reset. You can decide whether to run away with the movement speed boost or engage again with increased attack speed.
With the increased range from your ult, you can shoot over walls like the dragon or baron pit and even attack towers without getting hit.
If your enemies don't have vision while you are in camouflage and
Shen or
Orianna is ulting you, they won't see any animations.
Twisted Fate's ultimate will make you visible even when you're in camouflage.
You can use Q before recalling and complete your recall while in camouflage.
Join fights from an unseen spot or flank.
Your Q doesn't make you invisible; it's just camouflage. Nearby enemies will still be able to see you, so try to play around that radius.
Use W first to get additional poison stacks on your enemies, and as soon as you can't attack anymore, press E to maximize the damage.
Every time you get a kill or assist, your Q cooldown is reset. You can decide whether to run away with the movement speed boost or engage again with increased attack speed.
With the increased range from your ult, you can shoot over walls like the dragon or baron pit and even attack towers without getting hit.
If your enemies don't have vision while you are in camouflage and



You can use Q before recalling and complete your recall while in camouflage.
Summary and other guides



If you enjoyed my guide, I would appreciate a vote. Also, if you want to see more of my content, check out my other ADC guides.
Here are links to my other guides:
Caitlyn
Ezreal
Jinx
Xayah
Miss Fortune
Draven
Ashe
Jhin
Kalista
Kog'Maw
Lucian
Sivir
Tristana
Twitch
Varus
Vayne
Kaisa
Zeri
Samira
Aphelios
Senna
Nilah
Smolder
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