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Recommended Items
Runes:
Domination
Sorcery
+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+6 Armor
Spells:
Flash
Ignite
Items
Ability Order
Deadly Venom (PASSIVE)
Twitch Passive Ability
Threats & Synergies
Extreme
Major
Even
Minor
Tiny
None
Low
Ok
Strong
Ideal
Nautilus
Miss Fortune
Ideal
Strong
Ok
Low
None
Miss Fortune
Champion Build Guide
Why Twitch
Why should you pick
Twitch as your support? Twitch’s invisibility allows him to roam and surprise enemies, setting up ganks and securing kills. With his poison and slowness, Twitch can apply constant pressure on enemies, making them play cautiously (even if you are at spawn).
If you’re looking for a unique and cheesy way to dominate the map, Twitch support is the pick for you!
Twitch Support Runes
Absolute Focus and
Gathering Storm are jimmykoi’s preferred secondary, but you could also go
Presence of Mind and
Legend: Alacrity, they can help Twitch with his early game mana issues and provide him with additional attack speed to stack his poison more quickly.
Tips and Tricks
Laning Phase: During the laning phase, you want to get as much gold as possible by poking or AA’ing them enemy support/adc from the
Spectral Sickle item.
“While nearby an ally champion, damaging Abilities and Attacks against champions or buildings grant 20 gold.”
Most of the time though you want to look for as many successful roams to either mid, top or invades with your jungler.
Q Misdirection: Twitch can temporarily turn invisible and move more quickly thanks to his Q ability, Ambush. You can use this to deceive your opponents. For instance, you could activate
Ambush and move in one direction before quickly turning around and moving in the opposite direction to surprise your opponents to either escape or reposition for an attack.

More Tips Here.
Final Thoughts

This Twitch Build is highly inspired by the Challenger player jimmykoi.
Check out this Twitch Guide on my website, where I go more in-depth.
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