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Cassio is your archenemy, your nemesis! The pool will totally kill your flow, which basically stops you from using your W, E, R, Snowball and your Flash. This is total madness, which will make you moan many times when facing her.
Malzahar
Not as bad as Cassio, but if Malza decided to save his ult just for you, he also will be quite annoying. This problem can be solved buy getting the Quicksilver Sash, but leaves your build without the final item.
Shaco
Shaco also is one of the majorly annoying Champs to face against. If he is played well, his Boxes which fear will also mess with your flow. Even Oracle isn't much help, because you will dash in a lot from outer vision range.
Graves
Graves is another odd to fight against Champion. Not as bad as some others, but his Smoke can be annoying, if you want to dash around. You can't dash to what you cannot see.
Technically there still are many threats to Wu, even with this build. Especially CC and constant ranged poke can be hard to fight against. Basically if your team is getting poked to death, there is not much you can do.
Kalista
Kalista can be a lifesaver and/or your best ally in crime. No need to say she can save your ass many times or help to close gaps you cannot close alone. Usually you want her to save you though :D
Orianna
A little hard to pull off, but when in range, Ori can setup and ult with the ball on you to pull enemies towards you. Most of the time you dash out of her range though, but definitely worth mentioning for more experience Ori players.
Amumu
Amumu ult gives you a bit more time to strike with your ult. They also can't run away as fast as they would be able to without his ult. Not the best combo, but better than nothing.
Yuumi
Another okay Synergy can be Yuumi. She synergize well with most Champions, but I wouldn't call her a strong or ideal Synergy partner. Better than Amumu, but not as good as Ori and Kali.
Zilean
One honorable mention is Zilean. You can pick up his bombs before dashing in and also will be a valuable partner with his revive ult on you. Also his speed boost can be very useful. Overall Zilean might be a strong, but I still give it just an ok, because you will not be the center of his focus, since you are tanky enough with own exit abilities and not the main damage dealer.
Synergies
IdealStrongOkLowNone
Kalista
Kalista can be a lifesaver and/or your best ally in crime. No need to say she can save your ass many times or help to close gaps you cannot close alone. Usually you want her to save you though :D
Orianna
A little hard to pull off, but when in range, Ori can setup and ult with the ball on you to pull enemies towards you. Most of the time you dash out of her range though, but definitely worth mentioning for more experience Ori players.
Amumu
Amumu ult gives you a bit more time to strike with your ult. They also can't run away as fast as they would be able to without his ult. Not the best combo, but better than nothing.
Yuumi
Another okay Synergy can be Yuumi. She synergize well with most Champions, but I wouldn't call her a strong or ideal Synergy partner. Better than Amumu, but not as good as Ori and Kali.
Zilean
One honorable mention is Zilean. You can pick up his bombs before dashing in and also will be a valuable partner with his revive ult on you. Also his speed boost can be very useful. Overall Zilean might be a strong, but I still give it just an ok, because you will not be the center of his focus, since you are tanky enough with own exit abilities and not the main damage dealer.
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