Precision
In the precision tree we could take
Press the Attack for prolonged fights, definitively the best option if you aim for the late game, which is not what supports usually do. Still a good option agains heavy tank teams, especially if the enemy support is melee.
Fleet Footwork on the other had works better as a sustain rune against poke mages, which are Quinn's most dificult matchups.
Triumph simply outshines other runes in its branch.
Legend: Alacrity synergyses better with Quinn than its adyacent runes.
In the third slot there could be room for debate. I would say
Cut Down is generally better, while
Coup de Grace can work in specific cases.
Domination
In my opinion
Hail of Blades works too well with Quinn's kit, and is by far my favorite rune for her in the support role. It provides a lot of power in the early trades while in the late game offers somewhat of a synergy with
Navori Flickerblade.
Electrocute can work in certain scenarios, for example if you're looking to do those roams to mid frequently.
I preffer
Sudden Impact over
Cheap Shot because the later requires to be procced quite frequently to make good use of it.
Taste of Blood provides extra sustain, which is useful since you want to tank a lot of damage early game.
Deep Ward synergyses too well with Quinn support, since you have extremely easy access to th enemy jungle due to Quinn's
Heightened Senses and
Behind Enemy Lines.
Sixth Sense can be tricky with Quinn since sometimes you dont want to dismount to clear a ward, thus wasting the proc. I don't see the point in
Grisly Mementos, unless it turns to be OP and everybody runs it.
Relentless Hunter gives extra out of combat movement speed, which synergyses with Quinn's ultimate, but ultimately ends up being too redundant.
Treasure Hunter on the other hand provides extra gold for your slightly more expensive build.
Resolve
Aftershock can work pretty well with Quinn's as a support, but still the rune works better on melee units. Despite not the best primary runes in this tree for Quinn, it's still my prefered secondary tree for the extra survability.
Font of Life is definitively the best option in its line, providing extra sustain for your lane partner.
Bone Plating works better for sustained figths and for short trades, while
Second Wind performs best in poke matchups and fast trades.
Inspiration
Glacial Augment provides Quinn extra CC for peeling and initiation, a good rune to pick if your team lacks CC overall.
Cash Back isn't that great on support players since they make the less gold on the team.
Magical Footwear is generally good, but keep in mind you cannot power spike with T2 Boots early.
Biscuit Delivery in my opinion work better than
Time Warp Tonic
Cosmic Insight can be quite powerful if you decide to take both
Exhaust and
Ignite.
Jack of all Trades provides som extra power, and is quite easy to stack due to the support quest item.
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