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LoL Best Vayne ADC Build Guides 2025

Build guides for Vayne ADC on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne ADC builds. Create your own champion guide!



Season 3 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Build (Castellano) Chiste? De Que Me Hablas?

Build by julixan13 updated August 15, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

how to build vayne

Build by novittumieti updated August 20, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

My Vayne Build

Build by stefanelromania updated August 20, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

BATHSALTSX GUIDE TO #VAYNEMECHANICS

Build by Bathsaltsx updated August 19, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne the alcoholic

Build by zerixtah updated August 11, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

ArseniK - Vayne Bot

Build by ArseniK updated August 11, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Twerk L2 Vayne

Build by WingTribe updated August 8, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

EloHell escape - Vayne

Build by slija updated August 6, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne S3 (Taking it Bottom Lane)

Build by Arkshail updated August 5, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne the ultimate assassin...

Build by mrgeekuploader updated August 2, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

This shouldnt work....

Build by IncredibleEdible updated August 1, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Better Say It In Vayne. (Work In Progress)

Build by Nathankp99 updated August 1, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

ad vayne

Build by utkumoba1 updated July 31, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

My Vayne Guide

Build by Acidpunk updated July 31, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne - The Hyper Carry.

Build by JinxyBoi updated July 23, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Atack speed Vayne (S3)

Build by Damon Kruger updated July 20, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne (ADC) A Good Offence Is A Good Defence! ^^ (I ment bes

Build by ZT_NightmareCloud updated July 28, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Hard in the yard vayne s3 super killer.

Build by OriginalOP updated July 24, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Guide for Nicole's Vayne

Build by Onarco updated July 21, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

HardCore ADC by: .::|Subota|::.

Build by SrbinBreSrbenda updated July 21, 2013

League of Legends Champions:

Teamfight Tactics Guide