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LoL Best Vayne Build Guides 2025

Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!



Season 7 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

VAYNE FULL DAMAGE

Build by Doctor Hell updated July 16, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

THE CARRY

Build by Civic1992 updated July 4, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Guide Adc Botlane S7

Build by UrosRodic updated July 8, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

1v1 Vayne

Build by LunarMasterxXxXx updated July 7, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

VAYNE DEADLY BUILD

Build by HouYi updated July 7, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Unique Vayne by Anus Aaier

Build by muntos updated July 5, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

i will kill your tank

Build by uplift updated June 30, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

The Ultimate Vayne Guide

Build by thatcoolguy2000 updated June 29, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

ADC REAPER VAYNE | HYPERCARRY LIFESTEAL TANK [7.13]

Build by FreedomSenpai updated June 29, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne BOT Solo carry

Build by McPlayaCZ updated June 28, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Patch kys JUNGLE VAYNE

Build by UGANDANMILITIA updated June 17, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

The Level 7 Late game Goddess

Build by Diecrunch updated June 25, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Brutal DMG

Build by VaJeTrEx updated June 24, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

VAYNE BUILD FOR SEASON 7

Build by thanoszio updated June 10, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

I kill you because I enjoy it

Build by 8bitriko updated June 1, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Basic bronze vayne adc guide

Build by nnesh updated May 27, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Personal favorite Vayne build

Build by mihaiog updated May 26, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

MELTER VAYNE BUILD S7

Build by Darth Vedad updated May 23, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Strider789 Guide To Vayne

Build by strider789 updated May 22, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Top/Bot

Build by Deadshot099 updated May 21, 2017
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