LoL Best Vayne Build Guides 2025
Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!
Season 6 Builds
Vayne Patch 5.22 Preseason ADC guide
![]()
S6 Vayne Crtical Strike
S6 Vayne Crtical Strike
![]()
VAYNE BUILD ONLY
Vayne ADC S6
Season 5 Guides
![]()
The Art Of Assassination
![]()
The Unkillable Vayne
![]()
[Pt-Br] Vayne
![]()
Vayne, attack speed to victory.
![]()
Jungle Vayne: Solo Baron, Murder Tanks, get the Quadra
Jungle Vayne: Solo Baron, Murder Tanks, get the Quadra
Vayne - Build & Guide [ADC] [Patch 5.16]
![]()
A guide to stomp Yoloqueue Adventures! PATCH 5.14
![]()
Devouring Jungle Vayne
![]()
Marksman Vayne
![]()
Vayne the True Assassin [RGL Chief 5.12 ]
![]()
[S5] Vayne Guide - Their Final Hour (Detailed matchups inclu
![]()
evil_boh0h0's guide to Vayne (In progress)
![]()
Zc Caine's Best Vayne Guide
![]()
Playing Vayne be like
![]()
[Season 5] Vayne: ADC Goddess of Mechanics (Patch 5.9)
![]()
1v5 the enemy
Create Your Champion Build Guide
Share your strategy for your favorite champion with the largest League of Legends community!
CreateYour Guide!
