Hi! I´m not a top laner main but I thinkl that it would depend on the matchup. If you´re ahead I think that Drakhtar is the best item because it will help you to get more early kills (Panth is an early champion) but in the case that the matchup is kinda hard or you get camped I would recomend to take the Yoummu´s because it would save you more than once and the CD of this item is´nt very longer (about 50 secs) so you can come back to lane fastest and avoid a hard push for your enemies. This item helps you a lot to roam combined with his ult, so, summarizing, I think that it depends A LOT in the matchup and in your playstyle ^^ Hope I could help you a bit!
I can't see anything wrong with going Youmuu's Ghostblade into Duskblade of Draktharr into Black Cleaver though.