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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 1 Guides // Patch 25.04
9.5
569
Votes
84
LoL Champion Aatrox Build Guide
LoL Champion Aatrox Build Guide

[15.4] Aatrox Mega Guide 7m Master #1 worldwide MP OTP

Guide by Veng Shotz updated February 26, 2025
  • In-depth
9.2
18
Votes
1
LoL Champion Ryze Build Guide
LoL Champion Ryze Build Guide

Season 15 Ryze Guide Trisend3

Guide by Trisend3 updated February 28, 2025
9.2
298
Votes
27
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

EUW Challenger Kassadin Guide UPDATED 25.04

Guide by xracer02 updated March 3, 2025
9.2
600
Votes
34
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

[Season 15] BodyThoseFools' Rank 1 Challenger Azir Guide [In-depth] (10,000,000+ Mastery Points)

Guide by Body Those Fools updated March 1, 2025
  • In-depth
9.2
279
Votes
36
LoL Champion Kog'Maw Build Guide
LoL Champion Kog'Maw Build Guide

Diamond AP Kog'maw - Acid Reign [25.04]

Guide by Aqua Dragon updated February 20, 2025
  • In-depth
  • Off-Meta
8.9
133
Votes
18
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Diamond Tank Karthus - Slow Death [25.04]

Guide by Aqua Dragon updated February 20, 2025
  • In-depth
  • Off-Meta
8.8
14
Votes
1
LoL Champion Ahri Build Guide
LoL Champion Ahri Build Guide

[25.04] Straight to business - Master 80% WR Ahri

Guide by GentleJo updated February 22, 2025
8.6
33
Votes
5
LoL Champion Ziggs Build Guide
LoL Champion Ziggs Build Guide

A Comprehensive Ziggs Primer

Guide by Laimaudeja updated March 1, 2025
  • In-depth
8.6
66
Votes
9
LoL Champion Nasus Build Guide
LoL Champion Nasus Build Guide

[25.S1.4] Nasus Mid OTP - Simplest In-Depth Guide S2025

Guide by SurferKiller updated February 24, 2025
  • In-depth
8.6
25
Votes
5
LoL Champion Akshan Build Guide
LoL Champion Akshan Build Guide

[25.S1.4] In-Depth Akshan Guide [Mid/Top]

Guide by SanyGame updated February 20, 2025
  • In-depth
8.5
8
Votes
0
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

[25.04] Vlad simplefied by a low elo for low elo's

Guide by mitchellgamer12 updated February 20, 2025
  • In-depth
8.5
11
Votes
1
LoL Champion Ryze Build Guide
LoL Champion Ryze Build Guide

IN-DEPTH RYZE GUIDE ON RYZE *UPDATES EVERY PATCH*

Guide by v0ltage38 updated February 25, 2025
  • In-depth
8.3
22
Votes
5
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

15.1.4 Orianna

Guide by SeMike updated February 26, 2025
  • In-depth
8.1
14
Votes
3
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

Season 15 Syndra Guide Trisend3

Guide by Trisend3 updated February 26, 2025
Rating Pending
LoL Champion Karma Build Guide
LoL Champion Karma Build Guide

[25.04] The Essence of Karma: Mastering Fate

Guide by GentleJo updated February 20, 2025
7.3
81
Votes
26
LoL Champion Zeri Build Guide
LoL Champion Zeri Build Guide

[25.S1.4] ⚡️Get Zapped⚡️Zeri Ap Oneshot Build

Guide by Bambado updated February 20, 2025
7
6
Votes
2
LoL Champion Zed Build Guide
LoL Champion Zed Build Guide

Onzed Bruiser Zed Build S15

Guide by Chuleex updated February 27, 2025
  • In-depth
Rating Pending
LoL Champion Xerath Build Guide
LoL Champion Xerath Build Guide

Midlane - Dont go lost chapter...

Guide by Xerathiel updated March 3, 2025
  • In-depth
Rating Pending
LoL Champion Xerath Build Guide
LoL Champion Xerath Build Guide

[25.04]Rank 1 EUW/EUNE XERATH Dominating Midlane Guide

Guide by Hofibauer updated February 23, 2025
6
4
Votes
3
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

Katarina all good builds

Guide by 4milKata updated February 24, 2025

League of Legends Champions:

Teamfight Tactics Guide