It's time for the 2025 Season 1 Guide Contest! Create or update guides during the following 3 weeks to compete for the $3,750 prize pool. 🏆
LoL Best Senna Build Guides 2025
Build guides for Senna on MOBAFire. Find recommended items and runes by high ranked players to learn the best Senna builds. Create your own champion guide!
Season 10 Builds
![]()
Senna Ultimate Support 10.4 OP
Senna Ultimate Support 10.4 OP
![]()
Senna and Sona bot lane
Senna and Sona bot lane
![]()
[10.3] Senna Support Guide
![]()
Senna High Damage Support
![]()
Senna AD Carry
Senna AD Carry
![]()
[10.3] Senna support, ranged nasus
![]()
Senna Meta
![]()
[10.3] Korean Senna Adc/Top Lane
[10.3] Korean Senna Adc/Top Lane
![]()
Senna ADC 10.2
![]()
Senna carry supp
![]()
senna adc or support
![]()
[9.24] ADC/MID OR ANY OTHER LANE SENNA PROBUILD!
Senna
![]()
Senna MID/ADC
![]()
Just Try passiv + runes
![]()
Senna Jack of all trades build as support
![]()
Airtu Senna
top seena puild
![]()
[S9] Challenger Senna Mid! Ruining enemy laner's early game
![]()
[9.23] Tanky Support Senna
Create Your Champion Build Guide
Share your strategy for your favorite champion with the largest League of Legends community!
CreateYour Guide!
