* Liandry's is good against all enemy types and does everything decently without many weaknesses.
* Moonstone is strong against enemies with low burst or damage. This build is great at frontlining. Gargoyle can be built after after Archangel's if you need to be even tankier.
* Imperial Mandate is a more supportive build that is good at controlling fights and killing squishies, but struggles asainst bruiser and cannot kill tanks.
* Luden's is good at burst damage. It does best against squishy enemies, but can still kill bruisers or tanks.

Antiheal: If you need to, you can fit antiheal (Morellonomicon) in all builds 3rd or 4th item. You should only buy antiheal if the enemies have excessive healing that will prevent them from dying. Do not buy antiheal if your team does not have a source of damage. If you are playing the Moonstone build go Chemtech Putrifier instead of Morello. With Chemtech Putrifier, the healing from Moonstone on allies will give you both instant tier 2 antiheal, while Morello will require the enemy to fall below 50% health to apply tier 2 antiheal.
Armor Options: If the enemy has a physical damage threat then building armor is very beneficial. You can buy armor items at any point in the build Frozen Heart is the best option for armor and should always be built if you need armor. Zhonya's should only be built to counter Zed, Karthus, or any other unavoidable and extreme damage.
Magic Resist Options: MR can be built at any time but 1st item. Spirit Visage provides less MR, but amplifies your healing. Force of Nature is the strongest at stopping magic damage.
Demonic Embrace: This item is not as good as it seems and is only effective if the enemies are so tanky that you are struggling to deal damage.