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LoL Best Vayne ADC Build Guides 2025

Build guides for Vayne ADC on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne ADC builds. Create your own champion guide!



Season 12 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

🏹👓🔴LATE GAME AND CNCER🏹👓🔴 - Vayne Build

Build by KimeraBuilds04 updated November 30, 2021
Season 11 Guides
9.8
33
Votes
2
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

🏹 Improving your Vayne - [Patch 11.21 Ready] ✔️

Guide by 22Drift updated November 11, 2021
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Season 11 Vayne Guide

Guide by SillyRaccoom14 updated September 13, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Unique One Shot Invisible Vayne

Guide by Jeretar updated August 8, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne ADC Guide Season 11 v11.15

Guide by banewastaken updated July 27, 2021
8.8
31
Votes
5
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[11.13] Kewllkiddo's Diamond Season 11 Vayne Guide

Guide by Harambe Homie updated July 2, 2021
  • In-depth
8.9
144
Votes
10
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[11.12] THE ULTIMATE S11 GRANDMASTER Vayne Guide!

Guide by DoublefeedOP updated June 22, 2021
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

a

Guide by FaceLikeAStreamer updated June 1, 2021
8
8
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

A COMPLETE guide to Vayne, our favourite ADC!

Guide by ctm20141 updated March 18, 2021
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Guidelines for a Vayne Main.

Guide by SkittleBtw updated January 9, 2021
  • In-depth
9.1
17
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[PRE-SEASON] EUW Grandmaster rank 1 Vayne guide

Guide by pandorelol updated December 17, 2020
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Guide - Patch 10.24

Guide by LIKKEaBOSS updated November 28, 2020
Season 11 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne 11.17

Build by Zolmen updated August 28, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

vayne

Build by KUBACZ2332 updated August 19, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Season 11 - [11.15] - SkořicovýLupínek - Vayne ADC

Build by SkoricovyLupinek updated August 7, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Questionnable Vayne's build

Build by Dreamlan798 updated August 10, 2021
  • Off-Meta
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Best VAYNE guide season 11

Build by rarscooby updated July 21, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Movement speed Vayne

Build by bustas333 updated July 21, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

🛡TANK🛡 Vayne 100% WINRATIO (40min gameplay)

Build by Akageexe updated June 24, 2021
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Guia Vayne Season 11 Completo em PT-BR

Build by Hi im Hessel updated June 15, 2021

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