On patch 10.22, Annie's E now provides a shield instead of a damage reduction. Plus, you can put it on your allies now and it has longer range. Tibbers will always receive the shield everytime you press it.

[*] If your team wants to invade level 1, quickly upgrade W once you load into the game and use 2 W's in fountain and then 2 more while walking to the invade.

[*] Try to poke with autos and Q as much as possible to get gold from support item.

[*] When poking, use E to shield yourself from the damage they try to trade back.

[*] If you land a stun with Q, try to land W and then E to run back.

[*] Try not to all in until you have ult, unless it's a guaranteed kill.

[*] Try to stun their carries/backlines or as many people as possible.

[*] Flash+R to catch people off guard because it would be easy to see coming otherwise.

[*] You can press R to control Tibbers and make him tank tower shots and etc.

[*] Annie's autos have 625 range which is the second highest in the game next to Caitlyn (not including late game Senna, Tristana, or Jinx).

[*] At 3/4 stun charges, you can Q and while it's traveling to the opponent, hit W or E and the Q will stun them. (Use this to catch people off guard)

[*] When you're trying to stun a single target, most of the time it's better to Q than R, because even if they flash, they will be stunned.