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Recommended Items
Spells:
Heal
Flash
Items
Ability Order
Serpentine Grace (PASSIVE)
Cassiopeia Passive Ability
Introduction
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About Me Hey guys I'm twist. This is my second guide on Mobafire and i hope you guys will like it. I used to be a diamond player on both EUNE and EUW in solo queue, and managed to get into the 3v3 challenger division on EUNE in season 4. I started playing league since the beginning of season 2, took a break before this season, and now i'm back, ready to reclaim my rank. About the title I decided to make this guide because i saw the skill order R>E>W>Q being used even in one of the high-elo guides. For competitive games that is not the optimal way to play cassiopeia. What's In This Guide? In this guide i'll try to explain which masteries, runes and items you should use and some other things about cassiopeia. |

Cassiopeia is a very good champion in a solo lane, that's why i usually play her on the middle or top lane.
Cassiopeia has a very good passive (
Aspect of the Serpent) that offers us A LOT of ability power and cooldown reduction, an insane sustained damage because of her
Twin Fang ability, a decent amount of cc because of her
Miasma and
Petrifying Gaze, but she has some cons too. Poor mobility and the mana requirements are fair disadvantages, also she's very hard to master.
Cassiopeia has a very good passive (




Pros:
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Cons:
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Masteries
Offense
Most of the talents in this tree provide us with damage. The exceptions are:


which give us sustain.
Utility







Runes
I currently use three rune pages for cassiopeia.
Runes




Runes




Runes




Runes






Greater Mark of Magic Penetration - There are no better marks (reds) for a caster at the moment. They provide you with magic penetration, which increases your damage against enemies.
Greater Seal of Scaling Health - These seals provide you with some extra defense against any kind of champion. They become better than
Greater Seal of Health after level 6.
Greater Seal of Armor - If you know you are going to play against an enemy that uses attack damage more than ability power on the lane, you can go for these seals.
Greater Glyph of Scaling Ability Power - I find these to be the best glyphs for a caster, because your main role is to deal damage. This glyph becomes better than
Greater Glyph of Ability Power after level 7.
Greater Glyph of Magic Resist - If you are afraid of the enemy mage you will face on the lane you can go with these. They will provide you with extra survivability, but will reduce your damage.
Greater Quintessence of Ability Power - These provide your spells with a decent amount of extra damage. I also don't find another viable quintessence for a caster like annie. (maybe only the movement speed one)

Champion Abilities
So as you can see the order is R>E>Q>W. This is the way i play cassiopeia, and most of the professional players do.
Small tip: use ctrl+<spell key> to level an ability faster. For example if you just reached level 6 and a fight just started, instead of moving your mouse to that 'plus sign' press ctrl+r to level your ultimate. This is the smart-cast version to level abilities.
Petrifying Gaze(R)- Without doubt this is the best ability that cassiopeia has. Level this every time you can because it provides you with a strong CC and a decent amount of damage.
Twin Fang(E)- This is the second most important spell. It provides us with huge amounts of damage. Because we will use this spell a lot of times, the mana cost is a disadvantage, but our build will provide us with a lot of mana.
Noxious Blast(Q)- We usually use this spell for poking and before killing our target with the
Twin Fang spam. I choose to level this faster than
Miasma because it provides us with more damage.
Miasma(W)- Max this last because it increases mostly the strength of the slow. The damage increase is not that relevant.
Aspect of the Serpent(passive)- This passive is extremly good. The amounts of ability power and cooldown reduction provided are insane.

Summoner Spells
This summoner spell is a must have:
This spell can be used for ANYTHING. You can use this to run away,to chase, to jump over walls to escape, to reposition in teamfights. I can't tell you how many games i won just cause of this summoner spell.
After flash you can pick one of these spells:
Defensive choices:
+In the later stages of the game, escaping from a slow or stun might be more useful than getting a shield or some health back. -Doesn't protect your from suppression, knock-ups, knock-backs, grabs or flings. -I wouldn't recommend this one if you already plan on building ![]() |
+Provides us with extra health points and a movement speed boost. +Can aid our allies. +The health points we get don't disappear after 2 seconds. -Does not remove crowd control. (stuns, slows) -Is affected by grievous wounds. (healing reduction) |
+The shield is bigger than the amount of hp you get from heal. +Is not affected by healing reduction. -Doesn't remove crowd control. -The shield disappears after 2 seconds. -No movement speed boost. |
Utility choices:
+Very good against champions with a lot of burst damage. +Good for reaching your targets. (by slowing them down) -Sometimes as a carry, it might be more important to protect yourself than slowing down a certain target for 2.5 seconds. |
+Can get you where you are needed. (a very good spell if you are playing in the top lane) -It's harder to use than any other summoner spell. -Can't aid you in combat. |
Offensive choice:
+Good against targets that get healed. +Good early game when you might not have enough mana to finish your opponent. -Doesn't help you survive. -Sometimes you might not be in range to cast it on your target. (considering your skills range) |
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Core Items


Because Cassiopeia needs a lot of mana, we should buy one of these items. Seraph's offers us more damage and mana (that's why i pick this item most of the time), while rod of ages provides us with more health. Going for mana regeneration items like



Offensive items



If your enemies have magic resist items, you should go for void staff. Otherwise you have 2 options,


Defensive Items


The defensive item should be bought when you know you won't live a long time in the team-fights.



Hybrid Items





These items provide both defensive and offensive stats.
Zhonya's Hourglass is one of my favorite items from this category because it has such a strong active. The active is almost as good as the one from quicksilver sash or the shield from banshees' veil. If the enemy team lacks physical damage the armor might be a waste.
Abyssal Scepter is a good item. If your enemy laner deals mostly magic damage this could prevent your death during laning phase. One disadvantage is the low range of the magic resistance reduction aura that you get from this item.
Will of the Ancients can be used against opponents that deal hybrid damage (both magical and physical). This item can be really good on cassiopeia because of her sustained damage.
Rylai's Crystal Scepter and Liandry's Torment give you health and damage. You should go for rylai's or


Early Game
Try to harass your opponent with





Mid Game
If you just can't get a kill on your lane, try to either freeze the lane or push it and help the other lanes. This might be the perfect time to use your



If i am top and on the blue side of the map i usually ward this spot.

If i am top and on the red side of the map i usually ward this spot.

By warding those spots you can see the incoming ganks.
For mid: If only one side is warded, try to stay on that side of the lane.
For top: Try to stay as far away as you can from the river.
Late Game
In this part of the game, the most important thing is to stay around your team. Try to apply poison to your enemies because if you can't spam your


Gameplay videos
Below you have videos with professional players playing cassiopeia.
If you would like to see more videos with professional player in solo queue, you should take a look at this youtube channel. If you want to see a certain professional player or champion, comment in any of the videos.

If you would like to see me play casters (annie, cassiopeia, leblanc, lulu, syndra) on both summoners rift and twisted treeline you are more than welcome. If you would like to follow me, you can do that on my twitch page. (Link here)

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