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LoL Best Vayne ADC Build Guides 2025

Build guides for Vayne ADC on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne ADC builds. Create your own champion guide!



Season 3 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne ADC Guide by Gamehub1339

Build by Gamehub1339 updated November 3, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

A Tank ADC? Say What?

Build by ShadowDeniom updated November 3, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

ADC Vayne

Build by pokepie updated October 30, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Double Penta

Build by pokepie updated October 30, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne got fed

Build by Turbopung updated October 17, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Hyper carry Vayne

Build by bionixe updated October 5, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

How To Vayne

Build by CorporateBanana updated October 27, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Best build adc

Build by rossi1999 updated October 25, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

The true hunter

Build by ledangkhoalt updated October 23, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Hõrrôr Lullàby Vayne Fun Guide

Build by Horror Lullaby updated October 17, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Carry Destruction

Build by Kociou updated October 14, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

chase for win

Build by funambule updated October 12, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

AD Carry Vayne Bot Lane

Build by TheWDeadXx updated October 10, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Different But Powerful

Build by tyroneguy25 updated October 7, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Tanky killer Vayne(good vs enemy Vayne)

Build by imbra updated October 6, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

5s, Vayne - Too STRONK Can't Handle!

Build by TrollshotBG updated October 5, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne, the Monster

Build by SharpthorQ updated September 8, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Late game arrive prepare your anus

Build by valzakar updated September 22, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne, The Night Hunter

Build by Philipm0 updated September 15, 2013
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

My Vayne Build

Build by EvilDeath66X updated September 7, 2013
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