Best Vayne ADC Build Guides 2025 for LoL Patch 25.07

Rating Pending

Hypercarry Vayne ADC (Patch 10.23 -Preseason 11)
Build by Witz_btw updated November 12, 2020

Rating Pending

[PRESEASON] Vayne
Build by WILHO updated November 11, 2020

Rating Pending

VAYNE PRESEASON 11 GUIDE (VAYNE OTP) PATCH 10.23 (GOLD +)
Build by muscella updated November 18, 2020

Rating Pending

Magnum Explosion Vayne
Build by GabrielSanic updated November 13, 2020

Off-Meta

8.3

10
Votes
1

[10.22] In-Depth Vayne Build and Gameplay Guide
Guide by thelolbeast updated November 8, 2020

In-depth

Rating Pending

Ultimate Vayne Hard Carry Guide
Guide by Cam1304 updated October 30, 2020

7.7

11
Votes
3

Vibin with Vayne
Guide by PentasForDays updated July 16, 2020

7.7

11
Votes
3

[ADC] Vayne Guide Patch 10.14
Guide by Twiggymocha updated July 13, 2020

Rating Pending

Vayne-Kenshiro Hokuto late game w madness
Guide by Etrn updated June 28, 2020

Rating Pending

Vayne Guide | Build & Runes | 10.11 Patch [Updated]
Guide by Zoodyacc updated June 11, 2020

In-depth

9.5

28
Votes
2

[S10.10] ADC Vayne, the Night Hunter - Lategame has Arrived
Guide by atonementblade updated May 13, 2020

In-depth

Rating Pending

Vayne As Perfect As Udyr
Guide by Pingu Fugindo updated April 29, 2020

9.8

79
Votes
2

Midorima's Vayne Guide (Patch 9.1) | THE SAUCE
Guide by Midorima updated March 20, 2020

In-depth

8

8
Votes
1

(Portuguese Guide) High elo Main Vayne guide Patch 9.24 (g
Guide by Falllol updated December 16, 2019

8.8

17
Votes
2

Season 9 Vayne guide! Purge With Silver (9.23)
Guide by Laverenz updated November 27, 2019

In-depth

Rating Pending

Vayne [The Night Hunter] Champion Guide
Guide by mhsmhs123 updated December 7, 2019

7.8

7
Votes
1

[NEW]AssassinVayne's Special Build
Build by LSCaspen updated October 18, 2020

Rating Pending

ADC Vayne Guide Season 10
Build by Giuliano80 updated October 3, 2020

Rating Pending

The NOOB's ARAM/SR Vayne Guide [Read Notes for SR]
Build by Crash1025 updated October 2, 2020