Best Vayne ADC Build Guides 2025 for LoL Patch 25.05

7.9

10
Votes
2

Witches? I hate those guys...... [S3 Vayne Guide]
Guide by doctordowney updated March 8, 2013

In-depth

Rating Pending

Vayne - Van Helsing as a woman ! S3
Guide by SummonersRift updated February 18, 2013

Rating Pending

Dragonslayer Vayne
Guide by AdelaideHL updated February 20, 2013

Rating Pending

Vayne ADCarry Guide - THE NIGHT HUNTER
Guide by AdelaideHL updated February 1, 2013

8.6

19
Votes
3

Official HollaHolla Vayne Guide - Including Pure OG Crush
Guide by Doodlee updated September 3, 2013

In-depth

6.4

4
Votes
3

Trinity Force Vayne Patch 3.10a
Guide by AnabraHUN updated August 28, 2013

Rating Pending

Vayne: The Purifying Element
Guide by MontageMoment updated January 10, 2013

5.6

6
Votes
6

Who fed Vayne? (Updated to S3)
Guide by The Tofux updated April 10, 2013

In-depth

Rating Pending

The Final Hour
Guide by BestVayneNA updated January 25, 2013

Rating Pending

InfinityKnives Vayne build
Guide by infinityknives updated August 25, 2013

Rating Pending

Silent Gaming - Vayne Guide
Build by Silent Gaming updated November 17, 2013

Rating Pending

Vayne guide :P
Build by Roycer27 updated November 12, 2013

Rating Pending

Vayne Guide - The HyperCarry
Build by cyberfishh updated November 5, 2013

Rating Pending

Vayne ADC
Build by NekoDarky updated November 4, 2013

Rating Pending

Vayne ADC Guide by Gamehub1339
Build by Gamehub1339 updated November 3, 2013

Rating Pending

ADC Vayne
Build by pokepie updated October 30, 2013