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LoL Best Vayne ADC Build Guides 2025

Build guides for Vayne ADC on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne ADC builds. Create your own champion guide!



Season 10 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Svorn´s Vayne Guide

Build by Svorn4 updated March 12, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Dawn Dreamer ADC VAYNE BUILD

Build by Yummiez updated March 10, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[10.5] Kataclysm guide to Vayne, the Night Hunter

Build by STORMTGLIVE updated March 6, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne OP META

Build by C9 Tsol updated March 2, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne ADC / 10.3

Build by Daglow updated February 6, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne ADC | Basic Guide

Build by sHeeHeet updated February 12, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

OTP Vayne 44% winratio

Build by BartekVJ updated February 6, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne the queen

Build by Getronix x Cocaine updated February 5, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne all ways <3

Build by Getronix x Cocaine updated February 5, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Rageblade Hailblade Vayne

Build by gram_mobafire updated February 1, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne

Build by Ichaid updated January 30, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

vayne

Build by PlayerDavi updated January 9, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[Patch 9.24] Conqueror Vayne

Build by vaynePL420 updated January 7, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Carry Vayne Guide

Build by Venyax updated December 19, 2019
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Win every game as a vayne main

Build by Hitsige Henry updated December 30, 2019
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Omni Vayne ~Follow me on Twitch 6N1ghtmare6~

Build by 6N1ghtmare6 updated December 19, 2019
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Critical Vayne Guide

Build by Lee Azrael updated November 29, 2019
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne main : Ez Climb For Season 10

Build by PandaAintBurrito updated November 26, 2019
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Kelly's guide to vayne :)

Build by Yikes12345 updated November 29, 2019
Season 9 Guides
8.3
237
Votes
29
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[Top] Hunt Them Down | Vayne

Guide by qasddsa updated September 15, 2019
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