Best Vayne Build Guides 2025 for LoL Patch 25.05

8.8

17
Votes
2

Calculus Optimized Vayne
Guide by fanchessfan updated August 7, 2021

In-depth

Rating Pending

Unique One Shot Invisible Vayne
Guide by Jeretar updated August 8, 2021

7.1

19
Votes
9

[10.20] Top Lane Vayne: Abusing CDR
Guide by Seth346 updated July 29, 2021

In-depth

Rating Pending

Vayne ADC Guide Season 11 v11.15
Guide by banewastaken updated July 27, 2021

8.8

31
Votes
5

[11.13] Kewllkiddo's Diamond Season 11 Vayne Guide
Guide by Harambe Homie updated July 2, 2021

In-depth

8.9

144
Votes
10

[11.12] THE ULTIMATE S11 GRANDMASTER Vayne Guide!
Guide by DoublefeedOP updated June 22, 2021

In-depth

Rating Pending

{D2} Vayne Jungle Main
Guide by Mr.Dragon updated May 30, 2021

7.7

9
Votes
2

S11.7 Vayne the Lethal Vampire Hunter
Guide by dewdong updated April 2, 2021

6.8

16
Votes
9

S11.7 Vayne the Tank Engine
Guide by dewdong updated April 2, 2021

Off-Meta

8

8
Votes
1

A COMPLETE guide to Vayne, our favourite ADC!
Guide by ctm20141 updated March 18, 2021

In-depth

Rating Pending

Guidelines for a Vayne Main.
Guide by SkittleBtw updated January 9, 2021

In-depth

9.1

17
Votes
1

[PRE-SEASON] EUW Grandmaster rank 1 Vayne guide
Guide by pandorelol updated December 17, 2020

In-depth

Rating Pending

Vayne Guide - Patch 10.24
Guide by LIKKEaBOSS updated November 28, 2020

7.3

9
Votes
3

Vayne Carry All Lanes. Season 11 Updated.
Guide by HumoLoco updated November 22, 2020

Rating Pending

DUSKBLADE VAYNE
Build by M4TR1X updated November 16, 2021

Rating Pending

Vayne Mid
Build by MeechyDarko updated September 10, 2021

Off-Meta

Rating Pending

Vayne 11.17
Build by Zolmen updated August 28, 2021

Rating Pending

vayne
Build by KUBACZ2332 updated August 19, 2021

Rating Pending

Season 11 - [11.15] - SkořicovýLupínek - Vayne ADC
Build by SkoricovyLupinek updated August 7, 2021