LoL Best Cassiopeia Middle Build Guides 2025
Build guides for Cassiopeia Middle on MOBAFire. Find recommended items and runes by high ranked players to learn the best Cassiopeia Middle builds. Create your own champion guide!
Season 5 Builds
![]()
Cassiopeia Off Tank Guide Top, Mid
Cassiopeia Off Tank Guide Top, Mid
![]()
[AP] Unstopuble Mid
![]()
aka MonkeyFace
Season 4 Guides
![]()
Cass of Awesome Penetration!
![]()
Nightcrawl's S4 Revamped Diamond 2 Cassiopeia Guide
![]()
Cassiopeia - The Venomous Monarch
![]()
Ecco's Cassiopeia Guide
![]()
CassiOPeia, The Serpents Embrace
![]()
CassWhooping
![]()
Cassiopeia: The Serpent's Embrace (In-Depth)
Season 4 Builds
![]()
Medusa's Vengeance
![]()
olympic runner Cassiopeia
![]()
Cassiopeia, The Letal Snake
![]()
PeneTratic CassioPeia
![]()
Cassiopeia Guide
![]()
cassiopeia venom op
![]()
Cass OP
![]()
Cassiopeia
![]()
Cassiopeia
![]()
Cassiopeia Guide S4
Create Your Champion Build Guide
Share your strategy for your favorite champion with the largest League of Legends community!
CreateYour Guide!
